Andre Rinaldo Senna Garraffoni
Our research aims to study zoological taxa, such as Gastrotricha, Tardigrada, Kinorhyncha and Rotifera (also know as lesser-known protostome taxa) in oder to better understand the distinct evolutionary and biogeographical aspects of these freshwater and marine meiofauna organisms. Our ideia is integrate the distinct dimensions of meiofauna biodiversity - genetics, function, and phylogeny -based on in a broad framework that permits us to explore taxonomy, biogeography, molecular biology and evolutionary history
The current COVID-19 pandemic highlighted the vulnerability of our society to infections diseases. Whilst the current media focus is centered on SARS-CoV2, we must be prepared for the threat posed by drug-resistant parasites, fungi, and bacteria. The Synthetic Biology Laboratory (LaBS) was established in 2016 and is based on synthetic biology as a tool for drug discovery, using yeast and bacteria as hosts for heterologous expression and a platform for genome-wide screens. We have 3 well-established lines of investigation, which can further be improved and rapidly yield results. We are also introducing a novel highly ambitious line of research, taking advantage of our strong international collaboration network, for the development of novel antimicrobials inspired by secondary metabolites from native actinomycetes, filamentous fungi, or plant species.
Marcelo Carnier Dornelas
In the past our group has shown the conservation of the LEAFY gene function and expression patterns during vegetative-to-reproductive transition in tropical tree species. More recently we have been interested on the role of MADS-box genes in defining floral organ morphology and size, using Arabidopsis and passionfruit as models. Current work in our group focus on the molecular networks controlling plant development, taking into account the influences of genomic evolution and the effects of hormones such as auxins, cytokinins and gibberellins. Besides still being concentrated in studying gene function and expression patterns during vegetative-to-reproductive transition, we recently enlarged our interests into floral organ development and evolution as well as tropical fruit development.