ANIMAL GENETICS AND EVOLUTION
- Populations: gene and genotype frequencies.
- The Hardy-Weinberg principle: assumptions and conclusions.
- Inbreeding: biological aspects and the F coefficient.
- Genetic drift.
- Effective population size.
- Founder effect.
- Fate of mutations in populations.
- Interaction between migration and genetic drift.
- Natural selection: concepts and models.
- Genetic load
- Adaptation.
- Polymorphisms and the maintenance of genetic variability.
- Molecular evolution and the molecular clock hypothesis
- Notions of artificial selection and quantitative genetics.
- Quantitative trait loci.
- Heritability.
- Concepts of species.
- Mechanisms and genetic basis of reproductive isolation.
- Models of speciation.
- Haldane's Rule.
- Genetic differences that follow speciation.
Bibliography
Brown, T. A. 2006. Genomes. 3nd Edition, Garland Science. ISBN-13: 978-0815341383
Brown, T. 2011. Introduction to genetics: A molecular Approach. 1st Edition. Garland Science. ISBN-13: 978-0815365099
FALCONER, DS & TFC MACKAY. 1996. Introduction to Quantitative Genetics. 4th Edition. Benjamin Cummings. Essex. ISBN-13: 978-0582243026
Futuyma, D.J. 1997. Evolutionary Biology. 3rd Edition. Sinauer Associates. ISBN-13: 978-0878931897
FUTUYMA, DJ. 2013. Evolution. 3rd Edition. Sinauer Associates. ISBN-13: 978-1-60535-115-5
GRIFFITHS AJF; WESSLER SR; CARROLL SB; DOEBLEY J. 2010. Introduction to Genetic Analysis. 10th Edition. W. H. Freeman. ISBN-13: 978-1429229432
HARTL, DL & AG CLARK. 2006. Principles of Population Genetics. 4th Edition. Sinauer Associates. ISBN-13: 978-0878933082
HEDRICK, P. W. 2009. Genetics of Populations. 4th Edition. Jones and Bartlett Learning. ISBN-13: 978-0763757373
HERRON, JC & S FREEMAN. 2013. Evolutionary Analysis. 5th Edition. Benjamin Cummings. ISBN-13: 978-0321616678.
KLUG WS; CUMMINGS MR; SPENCER CA; PALLADINO MA. 2008. Concepts of Genetics. 9th Edition. Benjamin Cummings. ISBN-13: 978-0321524041.
Krebs, JE; Goldstein ES; Kilpatrick ST. 2009. Lewin's Genes X. Jones and Bartlett Learning. ISBN-13: 978-0763766320
Pierce, B. 2007. Genetics: A Conceptual Approach. 3rd Edition. W. H. Freeman. ISBN-13: 978-0716779285
Ridley, M. 2003. Evolution. 3rd Edition. Blackwell. ISBN-13: 978-1405103459
SHORROCKS, B. 1980. The genesis of diversity. 1979. University Park Press. ASIN: B0024BU15C
STEARNS, S. C. & R. F. HOEKSTRA. 2003. Evolution: an Introduction. 1st Edition Oxford University Press ISBN-13: 978-0199255634
STRICKBERGER, M. 2000. Evolution. Jones and Bartlett Publishers. ISBN: 0763710660
Watson, D. J., Baker, T. A., Bell, S. P., Gann, A., Levine M. Losick, R. 2010, 5th. ed. Molecular Biology of the Gene. Cold Spring Harbor Laboratory Press, SBN-13: 978-0805346350.
Watson, J. D., Myers R. M., Caudy, A. A. and Witkowski, A. 2007. 3rd Edition. DNA Recombinant DNA – A short course. W. H. Freeman. ISBN 0716728664
PLANT BREEDING AND GENETICS
- Genetic variability, germplasm bank and conservation of plant species
- Origin, evolution and reproductive systems in plants
- Selection and breeding of autogamous and allogamous plants
- Inbreeding, heterosis and genotype x environment interaction
- Transcription and RNA Processing
- Gene mutation and DNA repair mechanisms
- Transposable elements and extra chromosomal DNA
- Biotechnology applied to plant breeding
Bibliografia
Allard, R.W. Principles of Plant Breeding. 1960. John Wiley & Sons. ISBN-10: 047102315
Allard, R.W. Princípios do Melhoramento Genético de Plantas. Edgard Blücher Ltda.
FEHR, W.R. 1987. Principles of Cultivar Development : Theory and Technique (Vol 1). Macmillan Publishing Company. ISBN-10: 0963598902.
GRIFFITHS AJF; WESSLER SR; CARROLL SB; DOEBLEY J. 2013. Introdução à Genética. 10a Edição. Guanabara Koogan. ISBN: 9788527721912
GENETICS OF MICROORGANISMS
- Cytological Basis of Heredity
- Mendelian genetics gene interaction
- Chromosomal Theory of Inheritance
- Sex determination and sex linked inheritance
- Linkage groups and chromosomes
- Linkage, recombination and gene mapping in haploid and diploid organisms
- Pleiotropic gene.
- Multiple alleles.
- Gene and chromosomal mutations
- Cytoplasmic inheritance
- Giant chromosomes and the location of genes
- Molecular concept of the gene
- Genetic code and protein synthesis
- Recombination in bacteria: conjugation, transformation and transduction
- Gene regulation in prokaryotes
- Transcription in Prokaryotes.
- Gene mutation and DNA repair mechanisms
- Basic methodologies in genetic engineering
Bibliography:
Brown, T. A. 2006. Genomes. 3nd Edition, Garland Science. ISBN-13: 978-0815341383
GRIFFITHS AJF; WESSLER SR; CARROLL SB; DOEBLEY J. 2010. Introduction to Genetic Analysis. 10th Edition. W. H. Freeman. ISBN-13: 978-1429229432
Krebs, JE; Goldstein ES; Kilpatrick ST. 2009. Lewin's Genes X. Jones and Bartlett Learning. ISBN-13: 978-0763766320.
MICROBIOLOGY
- Morphology and structure of the bacterial cell
- Nutrition and bacterial metabolism
- Growth of bacterial cells and populations
- Media and conditions for the cultivation of microorganisms
- Microbiota and interactions between microorganisms
- Mechanisms of bacterial pathogenicity
- Control of microorganisms, chemical and physical agents
- Antibiotics and mechanisms of action
- Epidemiology of infectious diseases
- Diagnostic methods and conventional molecular
- Characteristic of filamentous fungi and yeast
- General characteristics of viruses
- Multiplication of animal viruses and bacteriophages
Bibliography:
MADIGAN, M.T.; MARTINKO, J.M.; PARKER, J. 2014. Brock Biology of Microorganisms. 14th Edition. Benjamin Cummings. ISBN-10: 321897390
TORTORA, G.J.; FUNKE, B.R.; CASE, C.L. 2009. Microbiology: An Introduction. 10th Edition. Benjamin Cummings. ISBN-10: 0321550072
MURRAY, P.R., ROSENTHAL, K.S., PFALLER, M.A. 2008. Medical Microbiology. Mosby. ISBN-10: 0323054706
Levinson, W. 2008. Review of Medical Microbiology and Immunology. 10th McGraw-Hill Medical. ISBN-13: 978-0071496209.
IMMUNOLOGY
- Natural or Innate Immunity
- Cells and tissues of the Adaptive Immune System
- Antibodies and antigens
- Antigen processing and presentation to T lymphocytes
- The Major Histocompatibility Complex
- Development of lymphocytes: rearrangement and expression of the antigen receptor genes
- Activation of T lymphocytes
- Activation of B lymphocytes
- Effector mechanisms of Cellular Immunity
- Effector mechanisms of humoral immunity
- Immune response against microorganisms
- Immune tolerance
- Hypersensitivities
- Autoimmunity and autoimmune diseases
- Manipulation of the immune response: control of undesirable response,
- immunity to tumors and production of vaccines.
- Laboratory techniques commonly used in immunology.
Bibliography
Abbas, A.K., Lichtman, A.H.H, Pillai, P. Cellular and Molecular Immunology. 2011. 7th Edition. Saunders. ISBN-10: 1437715281.
Murphy, K.M, Travers, P., Walport, M. 2007. Janeways´ Immunobiology. 2007. 7th Edition. Garland Science. ISBN-10: 0815341237
Male, M. Brostoff, J., Roth, D.B., Roitt, I. Immunology. 2006. 7th Edition. Mosby. ISBN-13: 978-0323033992
BIOINFORMATICS
- Nucleic Acids: Structure and Function
- Genetic code and protein synthesis;
- Regulation of gene expression;
- Replication and repair of genetic material;
- Mutation and natural selection;
- Genome projects, transcriptome, proteome, metagenome and structural genome;
- Fundamentals of programming: data types, selection and iteration, functions and procedures, data structures, fundamental algorithms;
- Analysis of algorithms;
- Relational database;
- Analysis of DNA and protein sequences;
- Sequence databases;
- Predictive methods using nucleotide and protein sequences;
- Sequence Polymorphisms;
- Blast and Fasta format;
- Multiple sequence alignment;
- Assembling of sequences
- Analysis of large-scale data (RNA-seq, ChIP-seq and sRNA-seq);
Bibliography
Lesk, A. Introduction to Bioinformatics. 2014. Oxford University Press. ISBN-13: 978-0199651566
Deonier, R.C. Tavaré, S., Waterman, M.S.. 2007. Computational Genome Analysis: An introduction. Springer. ISBN-13: 978-0387987859
Brown, T.A. Genomes. 2006. Wiley-Liss. 3rd edition. ISBN-13: 978-0815341383
Deonier, R.C. Tavaré, S., Waterman, M.S.. 2004. An Introduction to Bioinformatics Algorithms (Computational Molecular Biology). The MIT Press. ISBN-13: 978-0262101066
Gibas C, Jambeck P. Developing Bioinformatics Computer Skills. 2001. First Edition. O’Reilly & Associates. ISBN-13: 978-1565926646
Bessant C., Shadforth I., Oakley D. 2009. Building Bioinformatics Solutions with Perl, R and MySQL. Oxford University Press. ISBN-13: 978-0199230235