Agenda IB
Marcelo Carnier Dornelas
In the past our group has shown the conservation of the LEAFY gene function and expression patterns during vegetative-to-reproductive transition in tropical tree species. More recently we have been interested on the role of MADS-box genes in defining floral organ morphology and size, using Arabidopsis and passionfruit as models. Current work in our group focus on the molecular networks controlling plant development, taking into account the influences of genomic evolution and the effects of hormones such as auxins, cytokinins and gibberellins.
Marcelo Alves da Silva Mori
The main purpose of our lab is to identify and characterize molecular mechanisms involved in the aging process and in response to dietary interventions. We pay particular interest to understand how metabolism contributes to the genesis of age-related diseases like type 2 diabetes, cardiovascular diseases, and neurodegenerative diseases. We focus on the fat tissue - an important site of metabolic integration in multicellular organisms - and ask ourselves how this tissue responds to changes in energy balance and signals to other tissues to inform them about these changes.
Paulo Guimarães Gandra
Our primary research interest is the investigation of cellular mechanisms regulating skeletal muscle contractile activity and energy metabolism during stimulation and fatigue.
In our lab we are employing an intact single skeletal muscle fiber model that allows us to measure force generation and perform fluorescence microscopy to analyze intracellular parameters in real time during contractions at a single cell level.